Neuramis Deep (1 x 1ml)


This product is a sterile, clear, non-pyrogenic, viscoelastic gel, representing a new generation of dermal fillers made from non-animal sourced hyaluronic acid, created using innovative SHAPE technology. Designed for the reduction of moderate to severe wrinkles, leveling out nasolabial folds, and reshaping the nose, it also offers a push-up effect for the lips. Perfect for filling in deficits, the filler is biocompatible and safe for use with human body tissues.

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Items are shipped in 6 to 48 hours after the payment clears
(not counting weekends and holidays)


Neuramis Lidocaine is recommended for:

  • Smoothing out fine to moderate wrinkles.
  • Increasing lip fullness.
  • Enhancing skin firmness and thickness.
  • Boosting skin elasticity.
  • Moisturizing the skin.

Advantages of Neuramis Deep include:

  • Effective for filling deep wrinkles and replenishing volume.
  • Utilizes advanced SHAPE technology for a high purification level, featuring a dual-stage cross-linking process for purer hyaluronic acid, making Neuramis Deep both reliable and efficacious.
  • Immediate, safe improvements are seen right after application, enhancing skin structure and elasticity.
  • The product’s application is facilitated by the use of ultra-fine needles from TSK Laboratory (Japan) and the hyaluronic acid’s pliability, ensuring ease of usage and natural-looking results.
  • Manufactured with hyaluronic acid from Shiseido, a trusted Japanese supplier, Neuramis Deep’s quality is validated by approvals from the US FDA and the European Agency for the Quality Assurance of Medicines.
  • The effects of Neuramis Deep can last up to 12 months, varying by individual patient characteristics.

Ingredients of Neuramis Deep filler gel include:

  • Cross-linked hyaluronic acid at a concentration of 20.0 mg/mL.
  • Sodium dihydrogen phosphate dihydrate at 0.4 mg/mL.
  • Disodium hydrogen phosphate anhydrous at 1.2 mg/mL.
  • Sodium chloride at 8.3 mg/mL.
  • Bacteriostatic water, making up the balance to 1.0 mL.


The procedure involves administering the filler gel via into the dermal mid and deep layers.

Packaging Details:

The product comes in a cardboard box that houses a single-use glass syringe pre-filled with 1.0 ml of the solution, accompanied by two sterile, single-use 27G 1/2 (13 mm) UTW (Ultra Thin Wall) needles, a set of instructions, and two labels bearing the series and lot number for identification purposes.

*The UTW (Ultra Thin Wall) needle features a wider inner diameter compared to standard needles, facilitating smoother medication delivery and lessening the extrusion force required.

Additional information

Weight 0.06 kg

The decision to proceed with the treatment is made on a case-by-case basis.


The filler is designed for a one-time use.

Storage and handling of the product must adhere to the provided guidelines and consider the expiration date. Opening of the package should occur in the client’s view.

Potential Side Effects:

Experiencing slight swelling and redness for a day or two post-procedure is normal. Recovery from application marks may take up to one to two weeks in some instances.

Adhering to safety measures significantly reduces the risk of side effects. However, potential adverse reactions may include:

  • Swelling
  • Bruises
  • Inflammation (manifesting as redness, itching, or burning)
  • Formation of lumps or nodules at the application site
  • Discomfort

Though side effects are uncommon, their rarity doesn’t suggest any fault in the product’s effectiveness. Concern should arise if adverse symptoms continue beyond a week, at which point further medical evaluation is necessary.

Pre-Procedure Guidelines:

In the 1-2 weeks leading up to the procedure, the following are to be avoided:

  • Consumption of anticoagulant medication.
  • Undergoing aggressive cosmetic treatments such as chemical peels, laser treatments, or dermabrasion.
  • Participating in physical exercise.
  • Exposure to sunlight for prolonged periods.
  • Drinking alcoholic beverages.
  • Smoking.

Correction Process:

  • Removal of makeup and cleansing of the skin from dirt and dust particles.
  • Disinfecting the skin surface.
  • Mapping out the areas for application.
  • Administering the filler.
  • Applying an antiseptic solution for final cleansing.
  • Using an anti-inflammatory product post-procedure.
  • Optionally, an anesthetic cream may be applied if the filler lacks lidocaine or if the patient has a high sensitivity.

Techniques and Target Areas:

The choice of technique varies with the target area, including:

  • Single Puncture Technique: Ideal for enhancing the chin and cheekbones, utilizing a blunt-ended cannula instead of a needle for reduced trauma through a single entry point.
  • Spot Technique: Suitable for sensitive areas like the neck, around the mouth, and eyes, involving small, closely spaced usage to minimize discomfort.
  • Papular Technique: Aimed at improving the appearance of the lower two-thirds of the face, forehead, cheekbones, and cheeks, with the size and spacing of the papules tailored to the specific treatment goals.
  • Linear-Retrograde Technique: Used for filling wrinkles or increasing soft tissue volume, including lip augmentation, with the filler added in a continuous line as the needle is withdrawn at a 30-40-degree angle.

Neuramis Deep | Neuramis Deep Filler Usage Protocol:

  • Lip shape and volume correction: Utilizes a 27G x 13 needle with various linear and bolus techniques.
  • Nasolabial fold correction: A 27G x 13 needle or a 22G (25G) x 50 (70) cannula is employed, using linear-retrograde or fan techniques.
  • Nasolacrimal sulcus adjustment: A 27G x 13 needle or a 25G x 50 cannula is used with the linear-retrograde technique.
  • Cheek-maxillary enhancement: Either a 27G x 13 needle or a 22G x 50 (or 70) cannula is used, applying bolus or fan techniques.
  • Nasal shape modification: A 22G x 50 cannula is applied, utilizing linear-retrograde or bolus techniques.
  • Forehead enhancement: A 22G or 25G x 50 (or 70) cannula is used with fan or linear-retrograde techniques.

Disclaimer: Always read the detailed ingredients list on the back of the box or inside the included booklet. Be sure to read the included leaflet in regard to intended usage, proper application, safety procedures and, if applicable, possible counter indications and/or adverse effects. Make sure you are not allergic to any of the ingredients (certain products contain Lidocaine).